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  <titleInfo>
    <title>Development of vaccines</title>
    <subTitle>from discovery to clinical testing</subTitle>
  </titleInfo>
  <name type="personal">
    <namePart>Manmohan Singh</namePart>
    <namePart type="date">1964 Nov. 8-</namePart>
  </name>
  <name type="personal">
    <namePart>Srivasta, Indresh K.</namePart>
  </name>
  <name type="corporate">
    <namePart>ebrary, Inc</namePart>
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  <genre authority="marc">bibliography</genre>
  <genre authority="local">Electronic books.</genre>
  <originInfo>
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    <place>
      <placeTerm type="text">Hoboken, N.J</placeTerm>
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    <publisher>John Wiley &amp; Sons</publisher>
    <dateIssued>c2011</dateIssued>
    <dateIssued encoding="marc">2011</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">electronic</form>
    <form authority="gmd">electronic resource</form>
    <extent>xiii, 454 p., [8] p. of plates : ill. (some col.)</extent>
  </physicalDescription>
  <tableOfContents>Microbial vaccines design : the reverse vaccinology approach / Roberto Rosini, Michele A. Barocchi, Rino Rappuoli -- Design and development of recombinant vaccines with viral properties / Gerd Lipowsky, Martin F. Bachmann -- Tools for vaccine design : prediction and validation of highly immunogenic and conserved class II epitopes, and development of epitope-driven vaccines / Anne S. De Groot ... [et al.] -- Virus like-particle vaccines advantages and challenges / Ted M. Ross ... [et al.] -- Design platforms of nanocapsules for human therapeutics or vaccines / Masaaki Kawano ... [et al.] -- Designing immunogens for vaccine development in reference to HIV / Aemro Kassa ... [et al.] --</tableOfContents>
  <tableOfContents>Expression and purification of recombinant proteins for vaccine applications / Carlo Zambonelli, Deeann Martinez-Guzmann, and Indresh K. Srivastava -- DNA vaccines for infectious diesase / Samuel Stepenson, Manmohan Singh, Indresh K. Srivastava -- Developing stable cell lines for the production of vaccine antigens / Xiaotian Zhong ... [et al.] -- Spectroscopy of vaccines / C. Russell Middaugh, Sangeeta B. Joshi -- Biophysical characterization of protein antigens within vaccine formulations / Padima Malyala, Derek O'Hagan, Manmohan Singh -- Structural characteristics predict the stability of HIV / Zohar Biron ... [et al.] -- Selection of optimal adjuvants and product factors that affect vaccine immunogenicity / Wei Wang, Manmohan Singh -- Lyophilization and stabilization of vaccines / James Chesko ... [et al.] -- Effect of buffers and stabilizers on vaccine stability and efficacy / Shireesh P. Apte, Sydney Ugwu -- Selection of final product containers / Luis Baez, Adrian Distler -- From the lab to the clinic : filing a phase I IND for an investigational vaccine / Kenneth G. Surowitz.</tableOfContents>
  <note type="statement of responsibility">edited by Manmohan Singh, Indresh K. Srivastava.</note>
  <note>Includes bibliographical references and index.</note>
  <note>Electronic reproduction. Palo Alto, Calif. : ebrary, 2011. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.</note>
  <subject authority="lcsh">
    <topic>Vaccines</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Drug development</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Drug stability</topic>
  </subject>
  <classification authority="lcc">QR189 .D48 2011eb</classification>
  <classification authority="ddc" edition="22">615/.372</classification>
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