02107nam a22003374a 4500 ebr10186727 CaPaEBR m u cr cn||||||||| 070125s2007 ne a sb 001 0 eng 2007003418 101298156 DNLM 9780120887941 (hard cover : alk. paper) 0120887940 (hard cover : alk. paper) CaPaEBR CaPaEBR (OCoLC)162570604 QH447 .M88 2007eb Mushegian, Arcady R. Foundations of comparative genomics [electronic resource] / Arcady R. Mushegian. Amsterdam ; Boston : Academic Press, c2007. ix, 265 p. : ill. Includes bibliographical references (p. 238-257) and index. The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology. Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries. Genomics. Gene mapping. Physiology, Comparative. Electronic books. local ebrary, Inc. http://site.ebrary.com/lib/rucke/Doc?id=10186727 An electronic book accessible through the World Wide Web; click to view 145706 145706