03528nam a22003974a 4500 ebr10346883 CaPaEBR m u cr cn||||||||| 070117s2007 dcuaf sb 001 0 eng 2007002039 GBA740149 bnb 101297478 DNLM 013752605 Uk 9781555813031 1555813038 CaPaEBR CaPaEBR (OCoLC)646855073 QR177 .E59 2007eb 616.9/041 22 Enzyme-mediated resistance to antibiotics [electronic resource] : mechanisms, dissemination, and prospects for inhibition / editors, Robert A. Bonomo, Marcelo Tolmasky. Washington, D.C. : ASM Press, c2007. xviii, 357 p., [8] p. of plates : ill. (some col.). Includes bibliographical references and index. Overview of aminoglycosides and enzyme-mediated bacterial resistance: clinical implications / Robert A. Bonomo -- Aminoglycoside antibiotics / Kanchana Majumder ... [et al.] -- Structural aspects of aminoglycoside-modifying enzymes / Gerard D. Wright and Albert M. Berghuis -- Aminoglycoside-modifying enzymes: characteristics, localization, and dissemination / Marcelo E. Tolmasky -- rRNA methylases and resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone (MLSKO) antibiotics / Marilyn C. Roberts -- [Beta]-lactamases: historical perspectives / Karen Bush and Patricia A. Bradford -- Resistance mediated by penicillin-binding proteins / Malcolm G. P. Page -- Inhibition of class A [beta]-lactamases / Samy O. Meroueh, Jooyoung Cha, And Shahriar Mobashery -- Class B [beta]-lactamases / Gian Maria Rossolini and Jean-Denis Docquier -- Crystal structures of class C [beta]-lactamases: mechanistic implications and perspectives in drug design / C. Bauvois and J. Wouters -- Class D [beta]-lactamases / Franck Danel, Malcolm G. P. Page, and David M. Livermore -- Kinetics of [beta]-lactamases and penicillin-binding proteins / Moreno Galleni and Jean-Marie Fr�ere -- The pharmaceutical industry and inhibitors of bacterial enzymes: implications for drug development / David M. Shlaes, Lefa Alksne, and Steven J. Projan -- [Beta]-lactamase inhibitory proteins / Zhen Zhang and Timothy Palzkill -- Active drug efflux in bacteria / J�urg Dreier -- Overview of dissemination mechanisms of genes coding for resistance to antibiotics / Marcelo E. Tolmasky -- Conjugative transposons / Louis B. Rice -- The dissemination of antibiotic resistance by bacterial conjugation / Virginia L. Waters -- Bacterial toxin-antitoxin systems as targets for the development of novel antibiotics / Juan C. Alonso ... [et al.] -- Integrons and superintegrons / Robert A. Bonomo, Andrea M. Hujer, and Kristine M. Hujer -- The biological cost of antibiotic resistance / Dan I. Andersson ... [et al.]. Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries. Drug resistance in microorganisms. Drug resistance in microorganisms Genetic aspects. Microbial enzymes. Electronic books. local Bonomo, Robert A. Tolmasky, Marcelo. ebrary, Inc. http://site.ebrary.com/lib/rucke/Doc?id=10346883 An electronic book accessible through the World Wide Web; click to view 32364 32364