TY - BOOK AU - Bonomo,Robert A. AU - Tolmasky,Marcelo ED - ebrary, Inc. TI - Enzyme-mediated resistance to antibiotics: mechanisms, dissemination, and prospects for inhibition AV - QR177 .E59 2007eb U1 - 616.9/041 22 PY - 2007/// CY - Washington, D.C. PB - ASM Press KW - Drug resistance in microorganisms KW - Genetic aspects KW - Microbial enzymes KW - Electronic books KW - local N1 - Includes bibliographical references and index; Overview of aminoglycosides and enzyme-mediated bacterial resistance: clinical implications / Robert A. Bonomo -- Aminoglycoside antibiotics / Kanchana Majumder ... [et al.] -- Structural aspects of aminoglycoside-modifying enzymes / Gerard D. Wright and Albert M. Berghuis -- Aminoglycoside-modifying enzymes: characteristics, localization, and dissemination / Marcelo E. Tolmasky -- rRNA methylases and resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone (MLSKO) antibiotics / Marilyn C. Roberts -- [Beta]-lactamases: historical perspectives / Karen Bush and Patricia A. Bradford -- Resistance mediated by penicillin-binding proteins / Malcolm G. P. Page -- Inhibition of class A [beta]-lactamases / Samy O. Meroueh, Jooyoung Cha, And Shahriar Mobashery -- Class B [beta]-lactamases / Gian Maria Rossolini and Jean-Denis Docquier -- Crystal structures of class C [beta]-lactamases: mechanistic implications and perspectives in drug design / C. Bauvois and J. Wouters --; Class D [beta]-lactamases / Franck Danel, Malcolm G. P. Page, and David M. Livermore -- Kinetics of [beta]-lactamases and penicillin-binding proteins / Moreno Galleni and Jean-Marie Fr�ere -- The pharmaceutical industry and inhibitors of bacterial enzymes: implications for drug development / David M. Shlaes, Lefa Alksne, and Steven J. Projan -- [Beta]-lactamase inhibitory proteins / Zhen Zhang and Timothy Palzkill -- Active drug efflux in bacteria / J�urg Dreier -- Overview of dissemination mechanisms of genes coding for resistance to antibiotics / Marcelo E. Tolmasky -- Conjugative transposons / Louis B. Rice -- The dissemination of antibiotic resistance by bacterial conjugation / Virginia L. Waters -- Bacterial toxin-antitoxin systems as targets for the development of novel antibiotics / Juan C. Alonso ... [et al.] -- Integrons and superintegrons / Robert A. Bonomo, Andrea M. Hujer, and Kristine M. Hujer -- The biological cost of antibiotic resistance / Dan I. Andersson ... [et al.]; Electronic reproduction; Palo Alto, Calif.; ebrary; 2013; Available via World Wide Web; Access may be limited to ebrary affiliated libraries UR - http://site.ebrary.com/lib/rucke/Doc?id=10346883 ER -