workshop summary Patlak, Margie. Nass, Sharyl J. National Cancer Policy Forum (U.S.) Institute of Medicine (U.S.) ebrary, Inc text bibliography Electronic books. dcu Washington, D.C National Academies Press c2008 2008 monographic eng

electronic

electronic resource

xii, 124 p. : ill. (some col.). Introduction -- New clinical trial designs. Phase 0 trials -- Adaptive trial designs -- Targeting multiple pathways with multiple drugs -- Preclinical model systems -- Molecular imaging. Current and developing methods -- Challenges of molecular imaging -- Screening for predictive markers. The challenges of clinical validation -- Bioimaging predictive markers -- Clinical translation -- Panel discussion -- Costs of clinical trials. Regulatory costs -- Patient accrual -- Global outsourcing -- Time is money -- Public-private collaborations -- Regulatory issues. Regulatory barriers to innovation -- Patient advocacy perspective -- Regulation of in vitro diagnostics -- Regulatory issues in improving cancer clinical trials -- Reports from the case study discussion groups. Adaptive trial design -- Phase 0 trials -- Imaging -- Use of proteomics/genomics to assign therapy in lung cancer -- Use of genetics/genomics to assign therapy. National Cancer Policy Forum, Margie Patlack and Sharyl Nass, rapporteurs. Includes bibliographical references. Also available on the World Wide Web. Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries. n-us--- Cancer Treatment United States Clinical trials RC270.8 .I47 2008eb 362.196/994007 http://site.ebrary.com/lib/rucke/Doc?id=10235163 http://site.ebrary.com/lib/rucke/Doc?id=10235163 CaPaEBR 080709 ebr10235163