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  <titleInfo>
    <title>Cellular signaling and innate immune responses to RNA virus infections</title>
  </titleInfo>
  <name type="personal">
    <namePart>Brasier, Allan R.</namePart>
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  <name type="personal">
    <namePart>Garc�ia-Sastre, Adolfo.</namePart>
  </name>
  <name type="personal">
    <namePart>Lemon, Stanley M.</namePart>
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  <name type="corporate">
    <namePart>ebrary, Inc</namePart>
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    <place>
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    <publisher>ASM Press</publisher>
    <dateIssued>c2009</dateIssued>
    <dateIssued encoding="marc">2009</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
    <form authority="marcform">electronic</form>
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    <extent>xiii, 436 p. : ill. (some col.).</extent>
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  <tableOfContents>Role of toll-like receptors in the innate immune response to RNA viruses / Sin�ead E. Keating and Andrew G. Bowie -- Cytoplasmic pattern receptors and signaling in viral infections / Osamu Takeuchi and Shizuo Akira -- Mitochondrial antiviral signaling / Vijay G. Bhoj and Zhijian J. Chen -- Interferon regulatory factors and the atypical IKK-related kinases TBK1 and IKK? : essential players in the innate immune response to RNA virus infection / Meztli Arguello, Suzanne Paz, and John Hiscott -- Jak-stat pathway in response to virus infection / Joan E. Durbin -- Interferons and antiviral action / Christine L. White and Ganes C. Sen -- The nuclear factor-kB transcription factor pathway / Amer A. Beg and Xingyu Wang -- The nuclear factor-kB signaling network : insights from systems approaches / Allan R. Brasier -- Type 1 interferon signaling in shaping cellular innate and adaptive immunity to viral infection / Christine A. Biron -- Biological impact of type I interferon induction pathways beyond their antivirus activity / Bahram Razani ... [et al.] -- Human genetic factors involved in viral pathogenesis / Lennart Svensson and Elin Kindberg -- RNA virus families : distinguishing characteristics, differences, and similarities / Peter W. Mason and Frank Scholle --</tableOfContents>
  <tableOfContents>Rhabdoviruses and mechanisms of type I interferon antagonism / Krzysztof Brz�ozka and Karl-Klaus Conzelmann -- Filoviruses / Christopher F. Basler -- Inhibition of antiviral signaling pathways by paramyxovirus proteins / Antonella Casola ... [et al.] -- Suppression of innate immunity by orthomyxoviruses / Randy A. Albrecht and Adolfo Garc�ia-Sastre -- Bunyaviruses and innate immunity / Friedemann Weber and Richard M. Elliott -- Arenaviruses / Juan C. de la Torre -- Regulation of innate immunity by the flaviviridae / Brenda L. Fredericksen and Michael Gale Jr. -- Evasion of innate host antiviral defenses by picornaviruses / Stanley M. Lemon -- Togaviruses / William B. Klimstra and Kate D. Ryman -- Coronaviruses and arteriviruses / Krishna Narayanan and Shinji Makino -- Caliciviridae and astroviridae / Susana Guix and Mary K. Estes -- Innate immune responses elicited by reovirus and rotavirus / Barbara Sherry, John T. Patton, and Terence S. Dermody -- Summary and perspectives / Allan R. Brasier, Adolfo Garc�ia-Sastre, and Stanley M. Lemon.</tableOfContents>
  <note type="statement of responsibility">edited by Allan R. Brasier, Adolfo Garc�ia-Sastre, Stanley M. Lemon.</note>
  <note>Includes bibliographical references and index.</note>
  <note>Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.</note>
  <subject authority="lcsh">
    <topic>RNA viruses</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Natural immunity</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Cellular signal transduction</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Virus diseases</topic>
    <topic>Immunological aspects</topic>
  </subject>
  <classification authority="lcc">QR395 .C45 2009eb</classification>
  <classification authority="ddc" edition="22">579.2/5</classification>
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