02058nam a22003374a 4500 ebr10275759 CaPaEBR m u cr cn||||||||| 080703s2009 njuaf sb 001 0 eng 2008029607 101478147 DNLM 9780470412893 (cloth) 0470412895 (cloth) CaPaEBR CaPaEBR (OCoLC)317448271 RM301.3.G45 G457 2009eb 615/.7 22 Gene family targeted molecular design [electronic resource] / edited by Karen E. Lackey. Hoboken, N.J. : John Wiley & Sons, c2009. xvi, 347 p., [16] p. of plates : ill. (some col.). Includes bibliographical references and index. Drug discoveries by gene family / Karen E. Lackey -- G-protein coupled receptors / Stephen L. Garland and Tom D. Heightman -- Ion channels gene family : strategies for discovering ion channel drugs / Maria L. Garcia and Gregory J. Kaczorowski -- Integrins / David D. Miller -- Strategies for discovering kinase drugs / Jerry L. Adams ... [et al.] -- Protease-directed drug discovery / Richard Sedrani, Ulrich Hommel, and Jo�rg Eder -- Small-molecule inhibitors of protein-protein interactions : challenges and prospects / Adrian Whitty -- Transporters / Anne Hersey, Frank E. Blaney, and Sandeep Modi -- Nuclear receptor drug discovery / Hiroyuki Kagechika and Aya Tanatani -- Summary and comparison of molecules designed to modulate druggable targets in the major gene families / Karen E. Lackey. Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries. Pharmacogenomics. Drugs Design. Electronic books. local Lackey, Karen. ebrary, Inc. http://site.ebrary.com/lib/rucke/Doc?id=10275759 An electronic book accessible through the World Wide Web; click to view 6021 6021