02292nam a2200337 a 4500 ebr10662545 CaPaEBR m u cr cn||||||||| 121024s2013 njuadf sb 001 0 eng d 2012035755 9781118065631 (hardback) 9781118538180 (e-book) CaPaEBR CaPaEBR (OCoLC)828868892 RS419.5 .H542 2013eb 615.1/9 23 High-throughput screening methods in toxicity testing [electronic resource] / edited by Pablo Steinberg. Hoboken, N.J. : Wiley, 2013. xv, 552 p., [16] p. of plates : ill. (some col.) Includes bibliographical references and index. pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity. "High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"-- Provided by publisher. Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries. High throughput screening (Drug development) Toxicity testing. Electronic books. local Steinberg, Pablo. ebrary, Inc. http://site.ebrary.com/lib/rucke/Doc?id=10662545 An electronic book accessible through the World Wide Web; click to view 69892 69892