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  <titleInfo>
    <title>High-throughput screening methods in toxicity testing</title>
  </titleInfo>
  <name type="personal">
    <namePart>Steinberg, Pablo.</namePart>
  </name>
  <name type="corporate">
    <namePart>ebrary, Inc</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="local">Electronic books.</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">nju</placeTerm>
    </place>
    <place>
      <placeTerm type="text">Hoboken, N.J</placeTerm>
    </place>
    <publisher>Wiley</publisher>
    <dateIssued>2013</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">electronic</form>
    <form authority="gmd">electronic resource</form>
    <extent>xv, 552 p., [16] p. of plates : ill. (some col.)</extent>
  </physicalDescription>
  <abstract>"High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"--</abstract>
  <tableOfContents>pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.</tableOfContents>
  <note type="statement of responsibility">edited by Pablo Steinberg.</note>
  <note>Includes bibliographical references and index.</note>
  <note>Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.</note>
  <subject authority="lcsh">
    <topic>High throughput screening (Drug development)</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Toxicity testing</topic>
  </subject>
  <classification authority="lcc">RS419.5 .H542 2013eb</classification>
  <classification authority="ddc" edition="23">615.1/9</classification>
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  <identifier type="uri">http://site.ebrary.com/lib/rucke/Doc?id=10662545</identifier>
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