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  <titleInfo>
    <title>Drug discovery handbook</title>
  </titleInfo>
  <name type="personal">
    <namePart>Gad, Shayne C.</namePart>
    <namePart type="date">1948-</namePart>
  </name>
  <name type="corporate">
    <namePart>ebrary, Inc</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="local">Electronic books.</genre>
  <originInfo>
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    <place>
      <placeTerm type="text">Hoboken, N.J</placeTerm>
    </place>
    <publisher>Wiley-Interscience</publisher>
    <dateIssued>c2005</dateIssued>
    <dateIssued encoding="marc">2005</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
    <form authority="marcform">electronic</form>
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    <extent>xix, 1471 p. : ill.</extent>
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  <tableOfContents>Drug discovery in the 21st century: an introduction / Shayne C. Gad -- Natural products / Charles B. Spainhour -- Cancer cell proteomics using molecular aptamers / Weihong Tan, Zehui Cao, Dihua Shangguang -- Molecular similarity methods and QSAR models as tools for virtual screening / J�urgen Bajorath -- Systems biology: applications in drug discovery / Sean Ekins ...[et al.] -- High throughput flow cytometry / Larry A. Sklar ... [et al.] -- Combining NMR spectral information with associated structural features to form computationally non-intensive, rugged, and objective models of biological activity / Richard Beger, Dan A. Buzatu, Jon G. Wilkes -- Using Microsoft Excel as a laboratory data management tool / A. Erik Rubin, Mark F. Russo, William Neil -- The age of regulation / Sandy Weinberg, Gerald J. Whartenby -- Simultaneous screening of multiple cell lines using the CellCardtm system / Oren E. Beske -- Protein x-ray crystallography in drug discovery / Peter Nollert ...[et al.] -- Biological and chemistry assays available during drug discovery and developability assessment / Duane B. Lakings -- Strategies and methods in monitoring and targeting protein-protein interactions / Arianna Loregian, Giorgio Pal�u -- High throughput screening: evolution of technology and methods -- Martyn N. Banks ... [et al.] -- Metal-enhanced fluorescence: application to high-throughput screening and drug discovery / Kadir Aslan .. [et al,] -- Methods for the design and analysis of replicate-experiment studies to establish assay reproducibility and the equivalence of two potency assays / Brian J. Eastwood ... [et al.] -- Coupled luminescent methods in drug discovery: three-minute assays for cytotoxicity and phosphatase activity / Michael J. Corey, Robert J. Kinders -- Design and pharmaceutical applications of prodrugs / Tomi Jarvinen ... [et al.] -- GABA and glutamate receptor ligands and their therapeutic potential in CNS disorders / Ulf Madsen ... [et al.] -- Cardiac sarcolemmal ATP-sensitive potassium channel antagonists: novel ischemia-selective antiarrhythmic agents / George E. Billman -- Factors influencing the efficacy of mediator-specific anti-inflammatory, glucocorticoid and anti-coagulant therapies for sepsis / Peter C. Minneci ... [et al.] -- Combinatorial chemistry in the drug discovery process / Nathan T. Ross, Brian R. McNaughton, Benjamin L. Miller -- Herbal medicines and animal models of gastrointestinal diseases / C.H. Cho, J.K.S. Ko -- Endocrine and metabolic agents / Brian L. Furman -- Respiratory viruses / Paul D. Olivo -- Strategies in the design of antiviral drugs / Erik De Clercq, Piet Herdewijn -- Protein kinase inhibitors in drug discovery / Keykavous Parang, Gongqin Sun -- RNA-based therapies / Ingmar Hoerr, Steve Pascolo -- Novel imaging agents for molecular MR imaging of cancer / Dmitri Artemov, Zaver M. Bhujwalla -- Genomics-based drug discovery / Spyro Mousses -- Cancer drug discovery / Susan Mooberry.</tableOfContents>
  <note type="statement of responsibility">edited by Shayne Cox Gad.</note>
  <note>Includes bibliographical references and index.</note>
  <note>Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.</note>
  <subject authority="lcsh">
    <topic>Drugs</topic>
    <topic>Research</topic>
    <topic>Handbooks, manuals, etc</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Drug development</topic>
    <topic>Handbooks, manuals, etc</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Drugs</topic>
    <topic>Design</topic>
    <topic>Handbooks, manuals, etc</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Pharmaceutical chemistry</topic>
    <topic>Handbooks, manuals, etc</topic>
  </subject>
  <classification authority="lcc">RM301.25 .D784 2005eb</classification>
  <classification authority="ddc" edition="22">615/.19</classification>
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  <identifier type="uri">http://site.ebrary.com/lib/rucke/Doc?id=10304694</identifier>
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    <recordCreationDate encoding="marc">041115</recordCreationDate>
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