03210nam a22003974a 4500 ebr10296350 CaPaEBR m u cr cn||||||||| 080814s2009 njuaf sb 001 0 eng 2008036264 101481529 DNLM 9780470225554 (cloth) 0470225556 (cloth) CaPaEBR CaPaEBR (OCoLC)647763279 RS192 .D82 2009eb 615/.19 22 Drug efficacy, safety, and biologics discovery [electronic resource] : emerging technologies and tools / [edited by] Sean Ekins, Jinghai J. Xu. Hoboken, N.J. : John Wiley & Sons, c2009. xvi, 408 p., [16] p. of plates : ill. (some col.). Wiley series on technologies for the pharmaceutical industry Includes bibliographical references and index. Focus on the fundamentals : toward better therapeutic index prediction / Jinghai J. Xu and Li J. Yu -- High-throughput protein-based technologies and computational models for drug development, efficacy, and toxicity / Leonidas G. Alexopoulos, Julio Saez Rodriguez, and Christopher W. Espelin -- Cellular systems biology applied to preclinical safety testing : a case study of CellCiphr profiling / Lawrence Vernetti ... [et al.] -- Systems pharmacology, biomarkers, and biomolecular networks / Aram S. Adourian ... [et al.] -- Zebrafish models for human diseases and drug discovery / Hanbing Zhong, Ning-Ai Liu, and Shuo Lin -- Toxicity pathways and models : mining for potential side effects / Sean Ekins and Josef Scheiber -- Computational systems biology modeling of dosimetry and cellular response pathways / Qiang Zhang ... [et al.] -- Stem cell technology for embryotoxicity, cardiotoxicity, and hepatotoxicity evaluation / Julio C. Davila ... [et al.] -- Telemetry technology for preclinical drug discovery and development / Yi Yang --Nanotechnology to improve oral drug delivery / Mayank D. Bhavsar, Shardool Jain, and Mansoor M. Amiji -- Functional glycomics and the future of glycomic drugs / Ram Sasisekharan and Karthik Viswanathan -- Modeling efficacy and safety of engineered biologics / Jeffrey R. Chabot and Bruce Gomes -- Regulation of gene expression by small, non-coding RNAS : practical applications / Roman Herrara and Eric Tien -- Future perspectives of biological engineering in pharmaceutical research : the paradigm of modeling, mining, manipulation, and measurements / Jinghai J. Xu ... [et al.]. Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries. Drug development Technological innovations. Pharmaceutical technology. Biological products. Electronic books. local Ekins, Sean. Xu, Jinghai J. ebrary, Inc. Wiley series on technologies for the pharmaceutical industry. http://site.ebrary.com/lib/rucke/Doc?id=10296350 An electronic book accessible through the World Wide Web; click to view 77311 77311