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  <titleInfo>
    <title>Drug efficacy, safety, and biologics discovery</title>
    <subTitle>emerging technologies and tools</subTitle>
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  <name type="personal">
    <namePart>Ekins, Sean.</namePart>
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  <name type="personal">
    <namePart>Xu, Jinghai J.</namePart>
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  <name type="corporate">
    <namePart>ebrary, Inc</namePart>
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    <place>
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    <publisher>John Wiley &amp; Sons</publisher>
    <dateIssued>c2009</dateIssued>
    <dateIssued encoding="marc">2009</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
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    <extent>xvi, 408 p., [16] p. of plates : ill. (some col.).</extent>
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  <tableOfContents>Focus on the fundamentals : toward better therapeutic index prediction / Jinghai J. Xu and Li J. Yu -- High-throughput protein-based technologies and computational models for drug development, efficacy, and toxicity / Leonidas G. Alexopoulos, Julio Saez Rodriguez, and Christopher W. Espelin -- Cellular systems biology applied to preclinical safety testing : a case study of CellCiphr profiling / Lawrence Vernetti ... [et al.] -- Systems pharmacology, biomarkers, and biomolecular networks / Aram S. Adourian ... [et al.] -- Zebrafish models for human diseases and drug discovery / Hanbing Zhong, Ning-Ai Liu, and Shuo Lin -- Toxicity pathways and models : mining for potential side effects / Sean Ekins and Josef Scheiber -- Computational systems biology modeling of dosimetry and cellular response pathways / Qiang Zhang ... [et al.] --</tableOfContents>
  <tableOfContents>Stem cell technology for embryotoxicity, cardiotoxicity, and hepatotoxicity evaluation / Julio C. Davila ... [et al.] -- Telemetry technology for preclinical drug discovery and development / Yi Yang --Nanotechnology to improve oral drug delivery / Mayank D. Bhavsar, Shardool Jain, and Mansoor M. Amiji -- Functional glycomics and the future of glycomic drugs / Ram Sasisekharan and Karthik Viswanathan -- Modeling efficacy and safety of engineered biologics / Jeffrey R. Chabot and Bruce Gomes -- Regulation of gene expression by small, non-coding RNAS : practical applications / Roman Herrara and Eric Tien -- Future perspectives of biological engineering in pharmaceutical research : the paradigm of modeling, mining, manipulation, and measurements / Jinghai J. Xu ... [et al.].</tableOfContents>
  <note type="statement of responsibility">[edited by] Sean Ekins, Jinghai J. Xu.</note>
  <note>Includes bibliographical references and index.</note>
  <note>Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.</note>
  <subject authority="lcsh">
    <topic>Drug development</topic>
    <topic>Technological innovations</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Pharmaceutical technology</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Biological products</topic>
  </subject>
  <classification authority="lcc">RS192 .D82 2009eb</classification>
  <classification authority="ddc" edition="22">615/.19</classification>
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    <titleInfo>
      <title>Wiley series on technologies for the pharmaceutical industry</title>
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