03210nam a22003974a 4500001001200000003000800012006001900020007001500039008004100054010001700095016002000112020002600132020002300158040002100181035002100202050002300223082001600246245015100262260004800413300005600461490006500517504005100582505084500633505078601478533015202264650004902416650003102465650002502496655002902521700001702550700001902567710001702586830006602603856012602669999001702795ebr10296350CaPaEBRm        u        cr cn|||||||||080814s2009    njuaf   sb    001 0 eng    z  20080362647 z1014815292DNLM  z9780470225554 (cloth)  z0470225556 (cloth)  aCaPaEBRcCaPaEBR  a(OCoLC)64776327914aRS192b.D82 2009eb04a615/.1922200aDrug efficacy, safety, and biologics discoveryh[electronic resource] :bemerging technologies and tools /c[edited by] Sean Ekins, Jinghai J. Xu.  aHoboken, N.J. :bJohn Wiley & Sons,cc2009.  axvi, 408 p., [16] p. of plates :bill. (some col.).1 aWiley series on technologies for the pharmaceutical industry  aIncludes bibliographical references and index.0 aFocus on the fundamentals : toward better therapeutic index prediction / Jinghai J. Xu and Li J. Yu -- High-throughput protein-based technologies and computational models for drug development, efficacy, and toxicity / Leonidas G. Alexopoulos, Julio Saez Rodriguez, and Christopher W. Espelin -- Cellular systems biology applied to preclinical safety testing : a case study of CellCiphr profiling / Lawrence Vernetti ... [et al.] -- Systems pharmacology, biomarkers, and biomolecular networks / Aram S. Adourian ... [et al.] -- Zebrafish models for human diseases and drug discovery / Hanbing Zhong, Ning-Ai Liu, and Shuo Lin -- Toxicity pathways and models : mining for potential side effects / Sean Ekins and Josef Scheiber -- Computational systems biology modeling of dosimetry and cellular response pathways / Qiang Zhang ... [et al.] --0 aStem cell technology for embryotoxicity, cardiotoxicity, and hepatotoxicity evaluation / Julio C. Davila ... [et al.] -- Telemetry technology for preclinical drug discovery and development / Yi Yang --Nanotechnology to improve oral drug delivery / Mayank D. Bhavsar, Shardool Jain, and Mansoor M. Amiji -- Functional glycomics and the future of glycomic drugs / Ram Sasisekharan and Karthik Viswanathan -- Modeling efficacy and safety of engineered biologics / Jeffrey R. Chabot and Bruce Gomes -- Regulation of gene expression by small, non-coding RNAS : practical applications / Roman Herrara and Eric Tien -- Future perspectives of biological engineering in pharmaceutical research : the paradigm of modeling, mining, manipulation, and measurements / Jinghai J. Xu ... [et al.].  aElectronic reproduction.bPalo Alto, Calif. :cebrary,d2013.nAvailable via World Wide Web.nAccess may be limited to ebrary affiliated libraries. 0aDrug developmentxTechnological innovations. 0aPharmaceutical technology. 0aBiological products. 7aElectronic books.2local1 aEkins, Sean.1 aXu, Jinghai J.2 aebrary, Inc. 0aWiley series on technologies for the pharmaceutical industry.40uhttp://site.ebrary.com/lib/rucke/Doc?id=10296350zAn electronic book accessible through the World Wide Web; click to view  c77311d77311