02838nam a2200397 i 4500001001200000003000800012006001900020007001500039008004100054020002900095020002700124040003500151035002100186050002500207082001700232100002200249245010400271264006200375300005200437336002100489337002300510338003200533490002700565504005100592520112900643588004701772590014701819650002101966650004201987655002202029700002202051776021202073797001202285856012602297999001702423ebr10839238CaPaEBRm     o  d        cr cn|||||||||131029s2014    enkad   ob    001 0 eng|d  z9781118460702 (hardback)  a9781118762509 (e-book)  aCaPaEBRbengerdaepncCaPaEBR  a(OCoLC)86178912714aR853.C55bO34 2014eb04a610.72/42231 aO'Kelly, Michael.10aClinical trials with missing data :ba guide for practitioners /cMichael O'Kelly, Bohdana Ratitch. 1aChichester, West Sussex :bJohn Wiley & Sons Inc.,c2014.  a1 online resource (473 pages) :billustrations.  atext2rdacontent  acomputer2rdamedia  aonline resource2rdacarrier0 aStatistics in practice  aIncludes bibliographical references and index.  a"This book provides practical guidance for statisticians, clinicians, and researchers involved in clinical trials in the biopharmaceutical industry, medical and public health organisations. Academics and students needing an introduction to handling missing data will also find this book invaluable. The authors describe how missing data can affect the outcome and credibility of a clinical trial, show by examples how a clinical team can work to prevent missing data, and present the reader with approaches to address missing data effectively. The book is illustrated throughout with realistic case studies and worked examples, and presents clear and concise guidelines to enable good planning for missing data. The authors show how to handle missing data in a way that is transparent and easy to understand for clinicians, regulators and patients. New developments are presented to improve the choice and implementation of primary and sensitivity analyses for missing data. Many SAS code examples are included - the reader is given a toolbox for implementing analyses under a variety of assumptions"--Provided by publisher.  aDescription based on print version record.  aElectronic reproduction. Palo Alto, Calif. : ebrary, 2015. Available via World Wide Web. Access may be limited to ebrary affiliated libraries. 0aClinical trials. 0aClinical trialsxStatistical methods. 0aElectronic books.1 aRatitch, Bohdana.08iPrint version:aO'Kelly, Michael.tClinical trials with missing data : a guide for practitioners.dChichester, West Sussex : John Wiley & Sons Inc., 2014kStatistics in practicez9781118460702w(DLC)108392382 aebrary.40uhttp://site.ebrary.com/lib/rucke/Doc?id=10839238zAn electronic book accessible through the World Wide Web; click to view  c94935d94935